Synthetic Chemistry Interest Group

Virginia Tech Department of Chemistry

$$$Funding$$$: We thank Profs. Etzkorn, Kingston, Santos, and Carlier for providing refreshments for our meetings! We thank the National Science Foundation (Grant 0750006) for supporting Prof. Carlier's involvement in this series (see full acknowledgement below)

Organic synthesis is a key enabling technology for many research groups in VT Chemistry. New reactions of wide scope and high efficiency are being reported every week. But if you've never read the paper, or heard the talk, you can't use the reaction in your project!

To improve our individual synthetic "repertoires", we meet at 4:30 pm in Davidson 303 on the first Friday (generally!) of each month, September to May to hear presentations by students, post-docs and faculty on new synthetic methods. All are welcome, and refreshments are provided!

As we did in Academic Year 09/10, this year we will focus on informal "Journal Club"-type talks. These "Journal Club" talks will generally involve 3 individual presenters, each presenting a new "hot" synthetic methods paper (published within the last 3 months). We will also occasionally hold "Technology" talks to make members aware of advances in information retrieval and other areas likely to be of interest to the group. Finally we are fortunate to occasionally host outside speakers.

For more information, to sign up for a Journal Club or Technology presentations, contact Paul Carlier.

The template for Journal Club powerpoint presentations is available: Journal Club Template

Schedule:

Date	Speaker	Group(s)	Topic
9/3/10	Dr. Eugene Mazzola (FDA/U Md)	Special Speaker	Application of NMR Techniques in the Structural Elucidation of Complex Saponins from Edible Fruits
10/1/10	Astha Ming Gao Jielu Zhao	Carlier, Kingston	Metal Free Coupling of boronic esters and tosylhydrazones Decarboxylative addition of carboxylic acids to nitriles Ag-catalyzed late-stage fluorination
11/5/10	Derek Craft Mithun Raje Ken Knott	Carlier Santos	A new route to benzo[b]furans A tandem route to enantioenriched 1,3-aminoalcohols Pd-cat. cross-coupling of enantioenriched trifluoroborates
12/2/10	Brandon Thorpe Amy Fan Anton Sizovs	Santos Etzkorn Reineke	Copper-catalyzed CO2 fixation: paper 1, paper 2 Fe(III)-cat aza-Cope/Mannich route to pyrrolidines An umpolung route to amides
Feb 2011	No meeting this month
3/4/11	Ming Gao Neeraj Patwardhan Qiao-Hong Chen	Carlier	Mixed metal amides for controlled benzylic metalation A new deoxofluorination reagent Direct arene borylation with borenium ions
4/1/11	Eugene Camerino Jessica Wynn Amanda Nelson	Carlier Santos	Synthesis of o-cyano biphenyls by CN-directed C-H activation Organocatalytic hydroxymethylation of aldehydes Asymmetric allylic substitution via chiral contact ion pairs
5/6/11	Astha Wenyu Zhang Shraddha Patil	Carlier Santos Tanko	A new strategy to transform racemic starting materials to enantioenriched products Asymmetric organocatalytic monofluorovinylation Oxidation of alkyl trifluoroborates: tin-free radical chemistry

List of AY 09/10 presentations (with links to papers)

List of AY 08/09 presentations (with links to papers)

At the end of each year the presentations will be compiled and made available for download.

Compiled AY07/08 presentations (pdf, 226 p, 6.5 MB)

This material (seminar program, published presentations, and associated web pages) is in part based on work supported by the National Science Foundation under Grant 0750006 (Carlier, PI). Any opinions, findings, conclusions, or recommendations expressed in these materials are those of the author(s) and do not necessarily reflect those of the National Science Foundation.